ReviewiScience2026
Deciphering the neurotoxic effects of emerging pollutants: Bisphenols and phthalates as disruptors of brain function and mental health.
Review in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bisphenols and phthalates, ubiquitous plasticizers in everyday products, are endocrine-disrupting compounds (EDCs) that leach from matrices, contributing to widespread human exposure. These EDCs disrupt endocrine functions, affecting neurodevelopmental processes and increasing the risk of long-term adverse effects. This review examines the impact of bisphenol A (BPA) and phthalates on brain function and mental disorders. Exposure to these EDCs, particularly during critical developmental periods (perinatal and early childhood), induces changes in the neuroendocrine system, correlating with neurobehavioral disorders observed in puberty and later life. The alarming rise in global mental health disorders, especially among those under 18 (48.4% of reported cases), underscores the need to address environmental contributors like EDCs. While genetic and psychosocial factors are established contributors, emerging evidence highlights the role of EDCs in psychopathology. Further research and regulation of these ubiquitous compounds are essential to mitigate their impact on brain function and mental health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.