Evidence map›Paper›PMID 42256252›Full record

ArticleThe Lancet regional health. Southeast Asia2026

Seroprevalence of

Louise Pierneef, Munawir Muhammad, Gaby Wassenaar, Daniel Edbert, Hana Krismawati, Sitti Wahyuni, Soegianto Ali, Maria Mardalena Martini Kaisar, Paul Corstjens, Annemieke Geluk

Abstract read
In one paragraph

Article in The Lancet regional health. Southeast Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Louise PierneefLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Munawir MuhammadDepartment of Pharmacology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Gaby WassenaarLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Daniel EdbertDepartment of Microbiology, Faculty of Medicine, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Hana KrismawatiLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Sitti WahyuniDepartment of Parasitology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Soegianto AliMaster in Biomedicine Study Program, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Maria Mardalena Martini KaisarMaster in Biomedicine Study Program, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Paul CorstjensDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
Annemieke GelukLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Leprosy remains a significant public health issue in endemic regions, including areas in Indonesia. Transmission of Methods: We conducted a cross-sectional serosurvey among 637 children (ages 6-15) from schools in urban and rural areas of Sulawesi, Java, and Sumba, Indonesia. The PGL-I QURapid, a field-friendly and quantitative lateral flow assay, was used to detect anti-PGL-I IgM in fingerstick blood and plasma samples. Socioeconomic and health data, including helminth infection status and body-mass index z-scores (z-BMI), were also collected. Findings: The overall seroprevalence of anti-PGL-I IgM in children was 12.2% with significantly higher seroprevalence in rural (Southwest Sumba: 31.0%, Pangkajene: 11.2%) compared to urban areas (North Jakarta: 3.8%, Makassar city: 3.1%). Moreover, seroprevalence amongst children from low-SES schools was significantly higher (13.7%) than among those from high-SES schools (4.1%, Interpretation: Our findings demonstrate a high anti-PGL-I IgM seroprevalence among rural, low-SES, and helminth-infected children in Indonesia, indicating elevated levels of Funding: This study was funded by a grant from the Q.M. Gastmann-Wichers Foundation (AG) and an internal grant from Atma Jaya Catholic University of Indonesia (MMMK).

Indexed as

ChildrenHelminthsM. leprae infectionPGL-I QURapidRural vs. urbanTransmission

Identifiers

PMID42256252
PMCPMC13235328

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.