Evidence map›Paper›PMID 42256239›Full record

ReviewJHLT open2026

Surgical technique of donation after circulatory death heart procurement using direct procurement and hypothermic oxygenated perfusion preservation.

K Vandendriessche, J Brouckaert, K Van de Voorde, F Gaublomme, K Degezelle, J Van Cleemput, A Wallinder, F Rega

Abstract readReview
In one paragraph

Review in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

K VandendriesscheDepartment of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.
J BrouckaertDepartment of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.
K Van de VoordeDepartment of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.
F GaublommeDepartment of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.
K DegezelleDepartment of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.
J Van CleemputDepartment of Cardiology, University Hospitals Leuven, Leuven, Belgium.
A WallinderTransplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.
F RegaDepartment of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Donation after circulatory death (DCD) has re-emerged as a means of expanding the donor heart pool. Current clinical practice relies mainly on direct procurement followed by normothermic machine perfusion or on thoraco-abdominal normothermic regional perfusion. This paper details the practical aspects with an alternative strategy: direct procurement followed by hypothermic oxygenated perfusion (HOPE). Methods: Key technical considerations include prevention of bubble formation in albumin-containing solutions and early machine priming to avoid ischemic delays. The final acceptance of grafts is based on a functional warm ischemic time <30 min, satisfactory cardioplegic flush and anatomy, and stable, uneventful machine perfusion. Conclusion: Though this approach does not permit functional assessment of the graft, early results suggest that when strict donor and procedural criteria are observed, outcomes are favorable. Direct procurement of the DCD heart with HOPE offers a simplified, logistically efficient preservation method that avoids donor blood recirculation. Further studies are warranted to refine candidate selection and assess long-term results.

Indexed as

direct procurementdonation after circulatory deathheart transplantationhypothermic oxygenated perfusionmachine perfusion

Identifiers

PMID42256239
PMCPMC13234722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.