Evidence map›Paper›PMID 42256083›Full record

ArticleMaterials today. Bio2026

Mussel-inspired coaxial electrospun nanofiber membranes promote scarless oral mucosal repair by enhancing macrophage M2 polarization.

Junpeng Chen, Jinpeng Jiang, Wenyi Shen, Bingjie Xu, Haina Miao, Yangxi Cheng, Yi Zheng, Huiyong Zhu, Dan Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junpeng ChenDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jinpeng JiangDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wenyi ShenDepartment of Stomatology, Zhongshan City People's Hospital, Zhongshan, Guangdong Province, China.
Bingjie XuSchool of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an, China.
Haina MiaoDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yangxi ChengDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yi ZhengDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huiyong ZhuDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Dan YuDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The repair of oral mucosal defects is often hindered by the failure of traditional materials to maintain adhesion in humid, dynamic environments. Inspired by the wet-adhesion properties of mussels, we developed a biomimetic self-adhesive nanofibrous membrane via coaxial electrospinning. This membrane utilizes a polycaprolactone (PCL) core for mechanical strength and a dopamine (DA)-modified gelatin methacrylate (GelMA) shell for biocompatibility and adhesion. Experimental results demonstrate that the membrane possesses excellent mechanical properties, with a tensile strength of 2.52 MPa and a swelling degree of 554.6%. The incorporation of 2% DA significantly enhanced wet-adhesive strength to 30.53 kPa, allowing for stable adhesion to oral tissues for over 24 h.

Indexed as

Coaxial electrospinningDopamineMacrophage polarizationOral mucosal repairPPARγ

Identifiers

PMID42256083
PMCPMC13241875

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.