ArticleMaterials today. Bio2026
Bioinspired Melanoidin-Polyphenol nanocomplex for hair protection and mechanical reinforcement with antioxidant activity.
Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Ultraviolet (UV) radiation is one of the most pervasive environmental threats to biological interfaces, driving protein denaturation, structural weakening, and oxidative stress that collectively deteriorate the quality of skin and hair. Despite their widespread use, conventional UV filters are hindered by poor coatability, photoinstability, and safety concerns, underscoring the need for fundamentally new protection strategies. Herein, we report a bioderived melanoidin/tannic acid (MD/TA) nanocomplex that self-assembles into a robust photoprotective coating through synergistic interactions with polyphenols. By leveraging the intrinsic UVA absorption of melanoidin, the broad-spectrum UV shielding of tannic acid, radical-scavenging activity, and interfacial binding, the MD/TA complex forms uniform, durable, and antioxidant-active layers on hair fibers. Beyond surface protection, the coating reprograms oxidative stress responses by suppressing ROS accumulation, thereby restoring cuticle integrity and enhancing tensile resilience. At the molecular level, it activates endogenous antioxidant pathways (
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