Evidence map›Paper›PMID 42255921›Full record

ArticleDepression and anxiety2026

Bidirectional Associations Between Primary Caregivers' and Adolescents' Depressive and Anxiety Symptoms: An Intergenerational Actor-Partner Interdependence Model Analysis.

Hao Hou, Dan Luo, Shuzhen Zhu, Si Chen Zhou, Shu Yan, Yu Lei Jiang, Xiao Qin Wang, Qian Liu, Huijing Zou, Bing Xiang Yang

Abstract read
In one paragraph

Article in Depression and anxiety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hao HouDepartment of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China, rmhospital.com.
Dan LuoCenter for Wise Information Technology of Mental Health Nursing Research, School of Nursing, Wuhan University, Wuhan, Hubei, China, whu.edu.cn.ORCID 0000-0003-3079-3921
Shuzhen ZhuInstitute of Chronic and Non-communicable Disease Control and Prevention, Hubei Provincial Center for Disease Control and Prevention, Wuhan, Hubei, China, cdc.gov.
Si Chen ZhouCenter for Wise Information Technology of Mental Health Nursing Research, School of Nursing, Wuhan University, Wuhan, Hubei, China, whu.edu.cn.
Shu YanOffice of Psychosocial Services, Wuhan Mental Health Center, Wuhan, Hubei Province, China.
Yu Lei JiangCenter for Wise Information Technology of Mental Health Nursing Research, School of Nursing, Wuhan University, Wuhan, Hubei, China, whu.edu.cn.ORCID 0000-0003-3589-0464
Xiao Qin WangCenter for Wise Information Technology of Mental Health Nursing Research, School of Nursing, Wuhan University, Wuhan, Hubei, China, whu.edu.cn.
Qian LiuCenter for Wise Information Technology of Mental Health Nursing Research, School of Nursing, Wuhan University, Wuhan, Hubei, China, whu.edu.cn.ORCID 0000-0001-6833-6131
Huijing ZouCenter for Wise Information Technology of Mental Health Nursing Research, School of Nursing, Wuhan University, Wuhan, Hubei, China, whu.edu.cn.
Bing Xiang YangDepartment of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China, rmhospital.com.ORCID 0000-0002-0227-4342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Extensive research has focused on the top-down intergenerational transmission of psychopathological symptoms (ITP). However, little is known about the bidirectional and transactional dynamics of ITP between primary caregivers and their adolescent offspring in community-based samples. In particular, the moderating roles of caregiver and adolescent gender in these intergenerational associations remain underexplored. Methods: Between 2021 and 2022, a total of 1414 primary caregiver-adolescent dyads completed two waves of surveys assessing sociodemographic characteristics, as well as depressive and anxiety symptoms. The actor-partner interdependence model (APIM) was applied to examine the bidirectional transactional patterns of psychopathological symptoms within these dyads. Multiple-group comparison tests were conducted to evaluate the moderating effects of caregiver and adolescent gender on these associations. Results: Adolescents' depressive and anxiety symptoms significantly predicted subsequent depressive and anxiety symptoms in their primary caregivers. In contrast, only caregivers' anxiety symptoms were found to predict subsequent adolescents' depressive and anxiety symptoms. Multiple-group comparison tests indicated no significant moderating effects of caregiver or adolescent gender on the ITP. Conclusion: These findings suggest that depressive and anxiety symptoms may be mutually reinforced between adolescents and primary caregivers over time. A family-based approach to early identification and prevention could be a promising direction for interrupting escalating cycles of negative emotions across generations.

Indexed as

AnxietyCaregiversDepressionIntergenerational RelationsAdolescentAdultChildFemaleHumansMaleMiddle AgedModels, PsychologicalSex Factorsadolescentsanxietycaregiversdepressionintergenerational transmission

Identifiers

PMID42255921
PMCPMC13239181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.