Evidence map›Paper›PMID 42255806›Full record

ArticleCureus2026

Reassessment of Childhood Peanut Allergy Reveals Tolerance.

Shreena G Reddy, Vishaka R Hatcher, Charles K Miller

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shreena G ReddyPediatrics, Joint Base Charleston, Charleston, USA.
Vishaka R HatcherAllergy and Immunology, Wilford Hall Medical Center, San Antonio, USA.
Charles K MillerAllergy and Immunology, Mike O'Callaghan Military Medical Center, Nellis Air Force Base, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peanut allergy is commonly diagnosed in childhood and may persist as a medical label into adulthood despite the development of clinical tolerance, leading to potential misclassification and unnecessary dietary and occupational restrictions. We report a 19-year-old male patient with a childhood diagnosis of peanut allergy that precluded military enlistment in the United States despite years of reported asymptomatic peanut ingestion. Evaluation demonstrated persistent sensitization on skin prick testing, low-level peanut-specific IgE, and isolated sensitization to Ara h 8 on component-resolved diagnostics (CRD). Following structured reassessment, a supervised oral food challenge (OFC) was performed and tolerated without symptoms. The peanut allergy diagnosis was removed, and the patient was cleared for military accession. This case demonstrates that integration of clinical history, CRD, and OFC enables accurate risk stratification and safe delabeling of peanut allergy, with particular relevance in high-stakes settings.

Indexed as

allergen component testingclinical tolerancecomponent-resolved diagnosticsfood allergiesfood allergy delabelingoral food challengepeanut allergy

Identifiers

PMID42255806
PMCPMC13242224

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.