ArticleCureus2026
Acute Respiratory and Renal Failure Following Delayed Recognition of T-cell Lymphoblastic Leukemia in a Previously Healthy Child.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive pediatric hematologic malignancy that frequently presents with mediastinal involvement. Delayed recognition can result in rapid clinical deterioration due to airway compression, metabolic derangements, and treatment-related complications. We report the case of a previously healthy 12-year-old male who developed acute hypoxemic respiratory failure secondary to a large mediastinal mass initially treated as pneumonia, in whom imaging demonstrated a large anterior mediastinal mass with airway compression and a malignant right-sided pleural effusion with the diagnosis of T-ALL. The hospital course was complicated by severe tumor lysis syndrome resulting in oligo-anuric acute kidney injury, recurrent respiratory failure with acute lung injury, chemotherapy-induced pancytopenia, neutropenic enterocolitis, venous thrombosis, and persistent
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