Evidence map›Paper›PMID 42255751›Full record

ArticleCureus2026

Cannabis Expectancies as a Mediator in the Relationship Between Cannabis Use and Psychiatric Symptoms in Women With Post-traumatic Stress Disorder (PTSD) Symptoms.

Karina Villalba, Jennifer Attonito, Amie Newins

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karina VillalbaMedicine, University of Central Florida, Orlando, USA.
Jennifer AttonitoMedical Education, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
Amie NewinsPsychology, University of Central Florida, Orlando, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective This study examined whether cannabis expectancies mediate the relationship between lifetime cannabis use and symptoms of anxiety or depression among women who screened positive for post-traumatic stress disorder (PTSD). Method A total of 271 women completed an online survey assessing PTSD symptoms, lifetime cannabis use, anxiety and depression symptoms, and cannabis expectancies. Mediation analyses evaluated whether positive and negative cannabis expectancies explained the associations between lifetime cannabis use and anxiety or depression. Results The sample was predominantly White (238, 85%), with a mean age of 52.5 years (Mean±SD=12.2). Positive cannabis expectancies mediated the relationship between lifetime cannabis use and anxiety [indirect effect=0.35, Bootstrapped standard error of the effect estimate (BootSE)=0.15, 95% confidence interval (CI)=0.076 to 0.664] and depression (indirect effect=0.45, BootSE=0.19, 95% CI=0.12 to 0.88) such that women with longer cannabis use histories reported higher positive expectancies and higher levels of anxiety and depression. Conclusions Positive beliefs about cannabis's anxiolytic and antidepressant effects may influence both the duration of use and psychological outcomes among women with PTSD. These findings highlight the role of expectancies in shaping the mental health impact of cannabis use in this population.

Indexed as

anxietycannabiscannabis expectanciesdepressionptsd

Identifiers

PMID42255751
PMCPMC13236122

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.