Evidence map›Paper›PMID 42255749›Full record

ArticleCureus2026

Drusen-Like Deposit Choroidopathy in Systemic Lupus Without Glomerulonephritis Treated With a Dexamethasone Implant.

Nadyr A Damasceno, Soraya A Horowitz, Rodrigo S Pegado, Eduardo F Damasceno

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nadyr A DamascenoOphthalmology, Universidade Federal do Rio de Janeiro, Rio de Janeiro, BRA.
Soraya A HorowitzOphthalmology, Hospital Naval Marcílio Dias, Rio de Janeiro, BRA.
Rodrigo S PegadoOphthalmology, Instituto Brasileiro de Assistência e Pesquisa (IBAP), Niterói, BRA.
Eduardo F DamascenoOphthalmology, Universidade Federal Fluminense, Rio de Janeiro, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a 54-year-old woman referred to our clinic with a prior diagnosis of neovascular age-related macular degeneration (nAMD) and who had received three intravitreal aflibercept injections in the left eye (LE). Fundus examination revealed bilateral drusen-like deposits (DLDs) in the posterior pole, along with macular edema in the LE. Optical coherence tomography (OCT) demonstrated subretinal fluid, retinal pigment epithelium detachment (PED) in the LE, and bilateral DLDs and increased choroidal thickness. These findings raised suspicion of an inflammatory condition, prompting laboratory evaluation that supported the diagnosis of systemic lupus erythematosus (SLE). The ocular findings were subsequently reclassified as inflammatory choroiditis associated with DLDs, without evidence of lupus nephritis. Treatment with systemic corticosteroids, mycophenolate mofetil, and dexamethasone intravitreal implant in the LE resulted in progressive clinical improvement.

Indexed as

choroidopathydrusenoid-like depositsincreased choroidal thicknessnephritissystemic lupus erythematosus

Identifiers

PMID42255749
PMCPMC13236396

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.