ArticleCureus2026
Primary Signet-Ring Cell Carcinoma of the Colon: A Rare and Aggressive Tumor.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the case of a 50-year-old man who presented with progressive abdominal distension, weight loss, and ascites. Imaging revealed ileocecal wall thickening associated with peritoneal involvement. Colonoscopy demonstrated a circumferential, stenosing, ulcerative lesion in the cecum that was friable and could not be traversed by the endoscope. Histopathological examination of biopsy specimens confirmed signet-ring cell carcinoma. Upper gastrointestinal endoscopy showed no evidence of a gastric primary tumor, and computed tomography excluded distant metastasis, supporting a primary colonic origin. The patient was started on XELOX chemotherapy (capecitabine and oxaliplatin). This case highlights the diagnostic challenge of this entity, particularly in the presence of atypical features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.