Evidence map›Paper›PMID 42255732›Full record

ArticleCureus2026

Feasibility and Preliminary Outcomes of the Modified Makuuchi Incision in Urologic Oncology: A Single-Surgeon Case Series.

David Nelwan, Saeed Imam, Aaron Dahmen, Timothy Nywening, Andreas Karachristos, Noah L Nellis, Trushar Patel

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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

David NelwanDepartment of Urology, University of South Florida, Tampa, USA.
Saeed ImamDepartment of Urology, University of South Florida, Tampa, USA.
Aaron DahmenDepartment of Urology, University of South Florida, Tampa, USA.
Timothy NyweningDepartment of Surgical Oncology, University of South Florida, Tampa, USA.
Andreas KarachristosDepartment of Surgical Oncology, University of South Florida, Tampa, USA.
Noah L NellisDepartment of Urology, University of South Florida, Tampa, USA.
Trushar PatelDepartment of Urology, University of South Florida, Tampa, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe modified Makuuchi incision consists of a midline incision originating at the xiphoid process, extending caudally to the supra-umbilical region, then curving laterally as a "J/L" shape between the anterior superior iliac spine and the lowest rib. It affords not only ease of entry but also rapidity of closure, excellent exposure, and compatibility with prior abdominal incisions and any body habitus. Despite the potential benefits of the Makuuchi incision, it has had a limited role in urologic surgery. We present our experience with the utilization of the modified Makuuchi incision for large renal and adrenal tumors at our institution.

methodsSixteen cases utilizing the Makuuchi incision for genitourinary tumors were reviewed, all performed by a single urologist at our tertiary care institution. Data collected included patient demographics and characteristics, intraoperative metrics, and postoperative course.

resultsOur cohort consisted of seven females and nine males; 12 patients underwent right-sided incision, and four underwent left-sided incision. Twelve patients (75%) had renal cell carcinoma, and four had adrenal pathology. There was renal vein invasion/inferior vena cava thrombus in eight patients (50%). Table 1 summarizes the averages and ranges for the following data points in our 16 cases: patient age, BMI, tumor size, operative time, estimated blood loss, return of bowel function, post-anesthesia care unit oral morphine milligram equivalents (OME), and length of stay. Table 2 lists tumor size, staging, and the level of venous thrombus. There were neither intraoperative complications nor any incision-related postoperative complications.

conclusionsThe modified Makuuchi incision has been shown to be safe and feasible for large genitourinary tumors, with comparable outcomes to other incisions. Based on our cumulative operative experience, we conclude that the Makuuchi incision represents a feasible and adaptable surgical approach for complex urologic oncology cases and requires broad upper abdominal exposure.

Indexed as

adrenalgenitourinary tumorivc thrombusmodified makuuchi incisiononcologyrenalrenal cell carcinomaurology

Identifiers

PMID42255732
PMCPMC13242276

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