Evidence map›Paper›PMID 42255728›Full record

ArticleCureus2026

Delayed Chylothorax After Endometrial Carcinoma: A Case of Confirmed Thoracic Duct Leak Successfully Managed Conservatively.

Swetha Naveen, Thangaswamy Dhanasekar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Swetha NaveenRespiratory Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Thangaswamy DhanasekarPulmonology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chylothorax is an uncommon cause of pleural effusion resulting from the disruption or obstruction of the thoracic duct or its tributaries. Malignancy is a major non-traumatic cause, most commonly lymphoma, while involvement of gynecologic malignancies is exceedingly uncommon and largely limited to isolated case reports. We report the case of a 61-year-old woman with a prior history of poorly differentiated endometrial carcinoma treated in 2022 with total abdominal hysterectomy, bilateral salpingo-oophorectomy, and adjuvant brachytherapy, who presented three years later with progressive dyspnea, cough, anorexia, and weight loss. Imaging revealed recurrent left-sided pleural effusion. Diagnostic thoracentesis yielded milky fluid, and pleural fluid analysis demonstrated markedly elevated triglyceride levels with relatively low cholesterol, consistent with chylothorax, with negative microbiology and cytology for malignant cells. Intranodal lymphangiography confirmed an active thoracic duct leak into the left pleural cavity. Despite this, conservative management was pursued due to the patient's stable clinical status and preference to defer intervention, consisting of therapeutic thoracentesis and dietary modification with a low-fat diet supplemented by medium-chain triglycerides. This resulted in significant clinical and radiological resolution. This case highlights a delayed presentation of chylothorax following endometrial carcinoma and emphasizes a systematic diagnostic approach with individualized management, demonstrating successful conservative resolution despite a confirmed thoracic duct leak.

Indexed as

carcinoma endometriumchylothoraxlymphatic leaknon-traumatic chylothoraxpleural effusion

Identifiers

PMID42255728
PMCPMC13240974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.