Evidence map›Paper›PMID 42255680›Full record

ArticleFood science & nutrition2026

Hydroxy-α-Sanshools From

Tianting Luo, Yuping Zhu, Fangyan Xu, Jiao Xie, Huifang Chen, Likang Qin, Tingyuan Ren

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tianting LuoCollege of Brewing and Food Engineering Guizhou University Guiyang P. R. China.
Yuping ZhuSchool of Basic Medicine Guizhou Medical University Guiyang P. R. China.
Fangyan XuTongren Preschool Education College Tongren P. R. China.
Jiao XieKey Laboratory of Environmental Pollution Monitoring and Disease Control Guizhou Medical University Guiyang P. R. China.ORCID https://orcid.org/0000-0003-1125-9600
Huifang ChenCollege of Public Health Guizhou University of Traditional Chinese Medicine Guiyang P. R. China.
Likang QinCollege of Brewing and Food Engineering Guizhou University Guiyang P. R. China.
Tingyuan RenCollege of Brewing and Food Engineering Guizhou University Guiyang P. R. China.ORCID https://orcid.org/0000-0002-3251-268X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore whether hydroxy-alpha-sanshool (HAS) prevents obesity by modulating appetite and the gut microbiome, an obesity model was established using mice fed a high-fat diet. The food intake, body mass, feed efficiency and organ index of the mice were recorded, and the serum levels of GLP-1 and PYY were measured. The mRNA and protein expression of appetite-related genes in the small intestine and brain tissue were detected by real-time quantitative PCR and Western blotting, and the intestinal flora was analyzed by 16S rRNA gene sequencing. The results revealed that the body weight, food intake and feed efficiency of the mice were significantly reduced (4.28%, 14.46%, and 25.33%, respectively) and that the levels of GLP-1 and PYY were significantly increased (

Indexed as

dietary bioactive compoundsgut–brain axishigh‐fat diethydroxy‐α‐sanshoolZanthoxylum bungeanum Maxim

Identifiers

PMID42255680
PMCPMC13239063

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.