Evidence map›Paper›PMID 42255676›Full record

ArticleFood science & nutrition2026

Network Pharmacology and Integrated Experimental Evidence Demonstrate That Ophiopogonin D Suppresses Hepatocellular Carcinoma Progression via the UCK2-SLC7A11 Axis.

Yuxia Hao, Haris Muhammad, Yushi Wang, Yan Wang, Lu Cui, Jiajia Quan, Bing Xie, Xi Li

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuxia HaoThe Gastroenterology Department of Shanxi Provincial People's Hospital Taiyuan China.ORCID https://orcid.org/0009-0003-4451-4046
Haris MuhammadShanxi Provincial People's Hospital Shanxi Medical University Taiyuan China.
Yushi WangShanxi Provincial People's Hospital Shanxi Medical University Taiyuan China.
Yan WangShanxi Provincial People's Hospital Shanxi Medical University Taiyuan China.
Lu CuiShanxi Provincial People's Hospital Shanxi Medical University Taiyuan China.
Jiajia QuanShanxi Provincial People's Hospital Shanxi Medical University Taiyuan China.
Bing XieShanxi Provincial People's Hospital Shanxi Medical University Taiyuan China.
Xi LiCancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital Third Hospital of Shanxi Medical University Taiyuan China.ORCID https://orcid.org/0000-0002-6816-2562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) treatment faces significant challenges, including high toxicity and drug resistance. Ophiopogonin D, the active compound derived from the medicinal food material

Indexed as

ferroptosishepatocellular carcinoma (HCC)network pharmacologyophiopogonin DUCK2

Identifiers

PMID42255676
PMCPMC13240264

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.