ArticleACS omega2026
Mucoadhesive Nanoemulsion Enhances the Antineoplastic Potential of Naringenin in Bladder Cancer Cell Lines.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
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Abstract
Naringenin exhibits anticancer properties against various types of cancer. Bladder cancer is among the most prevalent cancers worldwide and is characterized by a high recurrence rate because of resistance to standard chemotherapy. Nanotechnology represents a prospective approach to counteracting the challenges associated with the therapeutic application of naringenin in the treatment of bladder cancer. The aim of this study was to evaluate the antineoplastic activity of naringenin in high-grade bladder cancer cell lines (J82 and UM-UC-3) and to develop nanoemulsions. The assessment of cellular toxicity was conducted using the sulforhodamine B method, clonogenic survival using crystal violet staining, cell migration by the wound healing assay, changes in the cell cycle using flow cytometry, and expression of the specific long noncoding RNAs
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