ArticleACS omega2026
Comprehensive Metabolomic Analysis of Saliva Using SWATH-DIA Reveals Systemic Metabolic Adaptations to Exercise.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Saliva is an accessible, noninvasive biofluid for real-time monitoring of physiological and metabolic changes. However, its potential to capture physical-exciton-induced biochemical responses has been limited by the metabolite identification depth and reproducibility of conventional metabolomics tools. In this study, we established a Sequential Window Acquisition of All Theoretical Fragment-Ion Spectra (SWATH-DIA)-based untargeted LC-MS metabolomics workflow for comprehensive profiling and relative quantitation of the salivary metabolome before and after physical exercise. Saliva samples were collected from 27 recreational runners before and immediately after a standardized 5 km run to investigate acute metabolic fluctuations in participants. The Zeno SWATH-DIA method enabled the simultaneous acquisition of precursor and fragment ion spectra across the full
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.