Evidence map›Paper›PMID 42255575›Full record

ArticleACS omega2026

Random Copolyester-Based Delivery Systems for Tear Protein Therapeutics in Ocular Surface Disorders.

Gloria Astolfi, Giulia Guidotti, Michelina Soccio, Franco Dominici, Debora Puglia, Nadia Lotti, Erika Ponzini, Silvia Tavazzi, Piera Versura, Luigi Fontana

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gloria AstolfiOphthalmology Unit, DIMEC, Alma Mater Studiorum University of Bologna, Bologna 40138, Italy.ORCID https://orcid.org/0000-0003-2079-5261
Giulia GuidottiDepartment of Civil, Chemical, Environmental and Materials Engineering, Alma Mater Studiorum Università di Bologna, Bologna 40131, Italy.ORCID https://orcid.org/0000-0001-6879-2989
Michelina SoccioDepartment of Civil, Chemical, Environmental and Materials Engineering, Alma Mater Studiorum Università di Bologna, Bologna 40131, Italy.ORCID https://orcid.org/0000-0003-3646-9612
Franco DominiciDepartment of Civil and Environmental Engineering, University of Perugia, 05100 Terni, Italy.
Debora PugliaDepartment of Civil and Environmental Engineering, University of Perugia, 05100 Terni, Italy.ORCID https://orcid.org/0000-0001-8515-7813
Nadia LottiDepartment of Civil, Chemical, Environmental and Materials Engineering, Alma Mater Studiorum Università di Bologna, Bologna 40131, Italy.ORCID https://orcid.org/0000-0002-7976-2934
Erika PonziniDepartment of Materials Science, University of Milano-Bicocca, 20126 Milan, Italy.ORCID https://orcid.org/0000-0002-3103-740X
Silvia TavazziDepartment of Materials Science, University of Milano-Bicocca, 20126 Milan, Italy.
Piera VersuraOphthalmology Unit, DIMEC, Alma Mater Studiorum University of Bologna, Bologna 40138, Italy.
Luigi FontanaOphthalmology Unit, DIMEC, Alma Mater Studiorum University of Bologna, Bologna 40138, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a polymeric drug delivery platform designed to address the limitations of conventional therapies for ocular surface and corneal disorders, such as dry eye disease (DED). Conventional treatments typically require frequent administration of eye drops, leading to poor bioavailability and patient adherence. We investigated the use of two random poly-(butylene succinate/diglycolate) copolymers, namely, P-(BS

Identifiers

PMID42255575
PMCPMC13234661

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.