Evidence map›Paper›PMID 42255539›Full record

ArticleACS omega2026

Synthesis and Cytotoxicity of Complex Betulinic Acid Amides.

Martina Wimmerová, Pavlína Kyjaková, David Šaman, Zdeněk Wimmer

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martina WimmerováDepartment of Chemistry of Natural Compounds, University of Chemistry and Technology in Prague, Technická 5, 16028 Prague 6, Czech Republic.
Pavlína KyjakováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo náměstí 2, 16610 Prague 6, Czech Republic.
David ŠamanInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo náměstí 2, 16610 Prague 6, Czech Republic.
Zdeněk WimmerDepartment of Chemistry of Natural Compounds, University of Chemistry and Technology in Prague, Technická 5, 16028 Prague 6, Czech Republic.ORCID https://orcid.org/0000-0002-4512-0116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main objective of this investigation was focused on the structure modification of betulinic acid to design novel cytotoxic compounds. The cytotoxicity of the amides of betulinic acid with several diamines was compared with that of the compounds bearing an additional amide bond formed by means of 4-methoxybenzoic acid. It was prepared by a green biotechnological approach from

Identifiers

PMID42255539
PMCPMC13234881

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.