Evidence map›Paper›PMID 42255254›Full record

ArticleEuropean urology open science2026

Optimizing the Diagnosis of Interstitial Cystitis/Bladder Pain Syndrome: An ESSIC Proposal.

Sachin Malde, Yoshiyuki Akiyama, Dick Janssen, Henry Lai, Jane Meijlink, Loredana Nasta, Michael Samarinas, Rob Moldwin, Claus Riedl, Jean Jacques Wyndaele and 1 more

Abstract read
In one paragraph

Article in European urology open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sachin MaldeKing's College London, London, UK.
Yoshiyuki AkiyamaShinshu University School of Medicine, Nagano, Japan.
Dick JanssenRadboudumc, Nijmegen, Netherlands.
Henry LaiWashington University in St. Louis, St. Louis, MO, USA.
Jane MeijlinkInternational Painful Bladder Foundation, Naarden, The Netherlands.
Loredana NastaItalian Interstitial Cystitis Association, Via Nomentana, Rome, Italy.
Michael SamarinasAssistant Professor of Urology, 2nd Urology Department, Aristotle University of Thessaloniki, Greece.
Rob MoldwinNorthwell Health, Zucker School of Medicine at Hofstra-Northwell, Lake Success, NY, USA.
Claus RiedlLandesklinikum Baden-Mödling, Austria.
Jean Jacques WyndaeleUniversity of Antwerp, Edegem, Belgium.
Mauro CervigniLa Sapienza University-Polo Pontino ICOT, Latina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a heterogenous symptom syndrome. Patients are often misdiagnosed, and current treatment algorithms do not promote an individualized approach to care. This latest international guideline from International Society for the Study of Interstitial Cystitis (ESSIC) provides a practical framework that all clinicians can use in daily practice to optimize the diagnosis and management of IC/BPS. Methods: An expert working group of the ESSIC held a series of structured meetings throughout 2023 and 2024 to achieve an international consensus on optimizing the diagnosis of IC/BPS. Detailed literature search of the PubMed database from inception until December 2024 was conducted. The nominal group technique, a semi-quantitative structured interview procedure, was used to identify and prioritize the aspects of assessment and diagnosis in which to achieve consensus. Key findings and limitations: Patients should be managed according to a standardized assessment as presented in this consensus. Cystoscopy is essential in the assessment of this condition, to exclude other conditions that may be the cause of the patient's symptoms and to classify patients into subtypes that can help to guide a personalized treatment approach. Cystoscopy features should be reported using the standardized ESSIC reporting tool. Bladder biopsy should be reported according to the ESSIC histological criteria. Conclusions and clinical implications: The diagnosis of IC/BPS requires specialist assessment. Cystoscopy and bladder biopsy should be performed by specialists in this field using the standardized ESSIC reporting criteria presented in this consensus document. The aim is to subtype patients into well-defined groups so that treatment can be individualized with the aim of improving outcomes for this debilitating condition.

Indexed as

Bladder pain syndromeDiagnosticsInterstitial cystitisLower urinary tract symptomsPelvic Pain

Identifiers

PMID42255254
PMCPMC13233585

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.