Evidence map›Paper›PMID 42255132›Full record

ArticleRSC advances2026

Novel benzothiazole-indole acetamides as potential anticancer agents: synthesis, biological evaluation, and

Nazanin Motamedi Shakib, Manica Negahdaripour, Mohammad Hosein Sayahi, Navid Dastyafteh, Zahra Dehghani, Mina Emami, Sajedeh Safapoor, Younes Ghasemi, Seyedeh Niloufar Ghafouri, Abbas Ghahramani and 4 more

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nazanin Motamedi ShakibSchool of Chemistry, College of Science, University of Tehran Tehran Iran.
Manica NegahdaripourPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences Shiraz Iran ranjbar_sa@sums.ac.ir.ORCID https://orcid.org/0000-0002-4265-1499
Mohammad Hosein SayahiDepartment of Chemistry, Payame Noor University Tehran Iran.
Navid DastyaftehCenter for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences Tehran Iran.
Zahra DehghaniPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences Shiraz Iran ranjbar_sa@sums.ac.ir.
Mina EmamiPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences Shiraz Iran ranjbar_sa@sums.ac.ir.
Sajedeh SafapoorEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran momahdavi@tums.ac.ir.
Younes GhasemiPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences Shiraz Iran ranjbar_sa@sums.ac.ir.
Seyedeh Niloufar GhafouriSchool of Chemistry, College of Science, University of Tehran Tehran Iran.
Abbas GhahramaniDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Kerman University of Medical Sciences Kerman Iran.
Mohammad Reza Mohajeri-TehraniEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran momahdavi@tums.ac.ir.
Bagher LarijaniEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran momahdavi@tums.ac.ir.
Mohammad MahdaviEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran momahdavi@tums.ac.ir.
Sara RanjbarPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences Shiraz Iran ranjbar_sa@sums.ac.ir.ORCID https://orcid.org/0000-0002-7675-4146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel benzothiazole-indole acetamides (9a-n) was designed and synthesized as potential anticancer agents, and their antiproliferative activities were evaluated against three cancer cell lines: A549 (human lung cancer), SW480 (human colon cancer), and HepG2 (human liver cancer). The most potent derivative identified was 2-(3-(benzo[

Identifiers

PMID42255132
PMCPMC13234837

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.