Evidence map›Paper›PMID 42255081›Full record

ArticleHealth science reports2026

The Effectiveness of Linezolid and Teicoplanin for Managing Infections After Burn Injuries: A Retrospective Study.

Abolfazl Zendehdel, Maryam Roham, Sanam Soltani, Amirali Jahanshahi, Somayeh Heidarizadi

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abolfazl ZendehdelInternal Medicine Department, Ziaeian Hospital Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-3186-8879
Maryam RohamSchool of Medicine, Antimicrobial Resistance Research Center Iran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0001-5406-709X
Sanam SoltaniPharmaceutical Science Research Center, Tehran Medical Sciences Islamic Azad University Tehran Iran.ORCID https://orcid.org/0009-0006-0345-2178
Amirali JahanshahiDr. Abidi Pharmaceutical Company Tehran Iran.ORCID https://orcid.org/0009-0004-5205-7401
Somayeh HeidarizadiDepartment of Anatomy, Faculty of Medicine Ilam University of Medical Sciences Ilam Iran.ORCID https://orcid.org/0000-0001-8934-7091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Gram-positive infections in burn patients present significant treatment challenges. This study compared the efficacy and safety of linezolid vs. teicoplanin for managing such infections in a clinical setting. Methods: We conducted a retrospective study involving 77 burn patients with confirmed Gram-positive infections at Shahid Motahari Hospital (2020-2022). Participants were allocated to: linezolid 600 mg BID ( Results: Linezolid demonstrated superior outcomes compared to teicoplanin: treatment duration was significantly shorter (5.68 ± 2.88 vs. 10.53 ± 6.86 days; mean difference -4.85 [95% CI -7.12 to -2.58], Conclusion: Linezolid showed significantly better efficacy than teicoplanin for Gram-positive burn infections, with reduced treatment duration and mortality while maintaining similar safety. Teicoplanin remains an alternative for specific cases.

Indexed as

antibioticburn injurieslinezolidS. aureusteicoplanin

Identifiers

PMID42255081
PMCPMC13239986

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.