ArticleHealth science reports2026
Cardiovascular Disease Risk Estimation Using Blood Biomarkers and the QRISK3 Stratification Tool: A Cross-Sectional Study in Jordan.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Aims: Cardiovascular diseases (CVD) are the leading cause of death in Jordan. This study aimed to estimate the prevalence of 10-year CVD risk as predicted by the QRISK3 tool and assess fibrinogen levels and lipid profile parameters as additional indicators of CVD risk in a Jordanian sample. Methods: This cross-sectional study was conducted in Amman, Jordan. Eligible participants aged 25-64 years provided informed consent and completed a baseline questionnaire. Blood samples were collected for fibrinogen and lipid profile analyses. This study followed the STROBE guidelines for reporting observational studies. Results: A total of 251 participants were recruited for this study. Among them, 78 (31.1%) had ≥ 10% QRISK3 score, and 36 (14.3%) had > 20% QRISK3 score. Active smokers had a higher prevalence of both ≥ 10% and > 20% QRISK3 scores compared to secondhand and never-smokers ( Conclusion: While the findings of this study cannot be generalized to the entire Jordanian population due to convenience sampling and the limited sample size, they highlight that a substantial proportion of participants are at elevated CVD risk. This underscores the importance of incorporating routine CVD risk screening into primary healthcare to identify high-risk individuals and enable early preventive interventions.
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