Evidence map›Paper›PMID 42254954›Full record

ArticleCase reports in pathology2026

Osteosarcoma in the Setting of Genetically Confirmed

Ava McKane, Morgan Noel, Andrew Hiatt, Cynthia Emory

Abstract read
In one paragraph

Article in Case reports in pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ava McKaneDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA, wakehealth.edu.ORCID https://orcid.org/0009-0001-8069-4545
Morgan NoelDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA, wakehealth.edu.ORCID https://orcid.org/0000-0003-3679-0473
Andrew HiattDepartment of Pathology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA, wakehealth.edu.ORCID https://orcid.org/0009-0003-0912-7438
Cynthia EmoryDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA, wakehealth.edu.ORCID https://orcid.org/0000-0002-5121-897X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Osteogenesis imperfecta (OI) is a group of skeletal dysplasias characterized by recurrent fractures and fragile bones. Two pathogenic variants in the Case Presentation: A 23-year-old female with Conclusion: Distinguishing OI-related skeletal changes from malignant bone tumors requires integration of clinical history, genetic testing, and careful pathologic evaluation via a multidisciplinary approach. While prior reports of concomitant osteosarcoma and OI have involved other subtypes, this case represents the first documented true co-occurrence in a patient with

Indexed as

case reportIFITM5osteogenesis imperfectaosteosarcoma

Identifiers

PMID42254954
PMCPMC13239498

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.