ArticleFrontiers in surgery2026
In-house 3D printed porous implants: does strontium-coating enhance osseointegration? An
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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10 authors.
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Abstract
Introduction: Early osseointegration is essential for the long-term success of uncemented custom-made prostheses, particularly in oncologic bone reconstruction where bone stock is compromised. Strontium (Sr) has demonstrated osteogenic potential, and Ti-Sr-O surface coatings may enhance local bone formation. Methods: This study evaluated whether Ti-Sr-O coating improves early osseointegration of 3D-printed porous Ti6Al4 V implants in a large-animal 2 mm gap model. Twenty female Romney-Texel sheep were randomized to receive either uncoated (P1) or Ti-Sr-O-coated (Sr-P1) cylindrical porous implants in the proximal tibia ( Results: All animals completed follow-up without implant-related complications. No significant differences were observed between groups in shear strength ( Discussion: Within the limitations of this gap model and four-week observation period, Ti-Sr-O coating did not enhance early mechanical fixation or osseointegration, highlighting that, within the constraints of this gap model and observation period, the study may be insufficient to detect the localized effects of Sr release, and that alternative experimental designs should be considered.
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