ArticlePulmonary circulation2026
Balancing Risk and Hope: Insights Into Pregnancy Outcomes in Pulmonary Arterial Hypertension.
Teresa Segura de la Cal, Carmen Pérez-Olivares, Raquel Luna-López, Irene Martín de Miguel, Alejandro Cruz-Utrilla, Olga Villar, Fernando Sarnago, Pedro Muñoz, Marina Santiago Sánchez, María Jesús López Gude and 5 more
Abstract read
In one paragraphArticle in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
15 authors.
Teresa Segura de la CalAdult Congenital Heart Disease Unit and Pulmonary Hypertension Unit, Department of Cardiology. ERN-Lung (European Reference Network on Rare Respiratory Diseases) Hospital Universitario 12 de Octubre Madrid Spain.ORCID https://orcid.org/0000-0003-0269-5574 Carmen Pérez-OlivaresDepartment of Cardiology Henares University Hospital Coslada Spain.
Irene Martín de MiguelAdult Congenital Heart Disease Unit and Pulmonary Hypertension Unit, Department of Cardiology. ERN-Lung (European Reference Network on Rare Respiratory Diseases) Hospital Universitario 12 de Octubre Madrid Spain.
Alejandro Cruz-UtrillaPulmonary Hypertension Unit, Department of Cardiology. ERN-LUNG (European Reference Network on Rare Respiratory Diseases). CIBERCV (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) Hospital Universitario 12 de Octubre Madrid Spain.ORCID https://orcid.org/0000-0002-3851-4037 Olga VillarDepartment of Obstetrics and Gynecology Hospital Universitario 12 de Octubre Madrid Spain.
Fernando SarnagoAdult Congenital Heart Disease Unit, Department of Cardiology Hospital Universitario 12 de Octubre Madrid Spain.
Pedro MuñozDepartment of Anaesthesiology Hospital Universitario 12 de Octubre Madrid Spain.
Marina Santiago SánchezDepartment of Anaesthesiology Hospital Universitario 12 de Octubre Madrid Spain.
María Jesús López GudeDepartment of Cardiac Surgery Hospital Universitario 12 de Octubre Madrid Spain.
Maite VelázquezCardiology Department and CIBERCV (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) Hospital Universitario 12 de Octubre Madrid Spain.
Laura ForcénDepartment of Obstetrics and Gynecology Hospital Universitario 12 de Octubre Madrid Spain.
Juan F DelgadoHeart Failure and Heart Transplant Unit, Department of Cardiology, and CIBERCV (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) Hospital Universitario 12 de Octubre Madrid Spain.
Fernando Arribas YnsaurriagaCardiology Department and CIBERCV (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) Hospital Universitario 12 de Octubre Madrid Spain.
Pilar Escribano-SubiasPulmonary Hypertension Unit, Department of Cardiology. ERN-LUNG (European Reference Network on Rare Respiratory Diseases). CIBERCV (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) Hospital Universitario 12 de Octubre Madrid Spain.ORCID https://orcid.org/0000-0002-6640-4839 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Pregnancy poses substantial risks for women with Pulmonary Arterial Hypertension (PAH). This study aimed to evaluate maternal and neonatal outcomes in a contemporary PAH cohort under modern management, specifically investigating whether vasoreactive status warrants distinct clinical recommendations. We conducted a retrospective, longitudinal cohort study of PAH pregnancies managed at our institution between February 2010 and December 2023, comparing clinical characteristics, maternal complications, long-term outcomes, and neonatal parameters between vasoreactive and non-vasoreactive patients. Among 29 patients, 8 underwent pregnancy termination, and 21 proceeded with the pregnancy; 7 (33.3%) of whom were vasoreactive. Non-vasoreactive patients experienced significantly higher rates of major complications (35.7% vs. 0%,
Indexed as
calcium channel blockersoffspringpregnancypulmonary arterial hypertensionvasoreactive
Identifiers
PMID42254880
PMCPMC13239620
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