Evidence map›Paper›PMID 42254708›Full record

ArticlePostepy psychiatrii neurologii2026

A novel missense variant Cys559Gly in

Karol Jastrzębski, Łukasz Kępczyński, Agnieszka Plucińska, Monika Kowalska-Gałecka, Agata Gajos

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Postepy psychiatrii neurologii, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karol JastrzębskiDepartment of Extrapyramidal Diseases, Medical University of Lodz, Poland.ORCID https://orcid.org/0000-0002-8651-8198
Łukasz KępczyńskiPolish Mother's Memorial Hospital Research Institute, Lodz, Poland.
Agnieszka PlucińskaNeurology Department, University Clinical Hospital No. 2, Medical University of Lodz, Poland.
Monika Kowalska-GałeckaRehabilitation Department, University Clinical Hospital No. 2, Medical University of Lodz, Poland.
Agata GajosDepartment of Extrapyramidal Diseases, Medical University of Lodz, Poland.ORCID https://orcid.org/0000-0002-3753-6197

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report a novel Case description: Two affected sisters with dementia and ischemic stroke (only the proband) in their medical history, and the pro- band's daughter with migraine without aura underwent clinical and imaging evaluations. Magnetic resonance imaging revealed typical CADASIL lesions in both sisters. Next-generation sequencing and targeted Sanger sequencing were performed to link the phenotype to a variant in the Comment: Sequencing data revealed a likely pathogenic variant in the

Indexed as

CADASILmigrainepathogenic variantsmall vessel disease

Identifiers

PMID42254708
PMCPMC13237739

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.