Evidence map›Paper›PMID 42254610›Full record

ArticleFrontiers in public health2026

Seasonal summer stress affects systemic redox homeostasis: a longitudinal marker analysis in healthy adults.

Hong Zhou, Jiachen Dai, Yuemei Zhang, Wenwen Tang, Yingying Ren, Xinming Zhang, George H Lorimer, Hasan Bayram, Reza A Ghilad, Junqiang Xu and 2 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hong Zhou *National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, China.
Jiachen Dai *National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, China.
Yuemei ZhangNational "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, China.
Wenwen TangNational "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, China.
Yingying RenNational "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, China.
Xinming ZhangNational "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, China.
George H LorimerDepartment of Chemistry, University of Maryland, College Park, MD, United States.
Hasan BayramDepartment of Pulmonary Medicine, School of Medicine, Koc University, Istanbul, Türkiye.
Reza A GhiladDepartment of Chemistry, North Carolina State University, Raleigh, NC, United States.
Junqiang XuHubei Center for Disease Control and Prevention, Wuhan, China.
Fanghua MeiHubei Center for Disease Control and Prevention, Wuhan, China.
Jun WangNational "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: As global climate change and urbanization accelerate, summer heat waves are becoming more frequent and intense, posing an increasing threat to human health. However, previous studies have predominantly focused on the impact of summer high temperatures on people with pre-existing diseases, with few reports investigating their effects on healthy individuals. Redox balance is a core foundation of human health and is closely linked to changes in ambient temperature. Methods: The present study enrolled 330 healthy volunteers from four cities in Hubei Province, China. Fasting serum samples were collected during spring (mild temperatures) and summer (high temperatures), and the levels of six redox markers were measured and analyzed: nitrite (NO Results: The results revealed that under Discussion: Furthermore, significant methodological biases may arise if the seasonal variations in serum MDA levels are not taken into account when researching in this area. These findings provide a novel direction for investigating the impacts of high summer temperatures on health and may lay the foundation for guiding public health practices.

Indexed as

HomeostasisHot TemperatureOxidative StressSeasonsStress, PhysiologicalAdultAntioxidantsBiomarkersChinaFemaleHealthy VolunteersHumansLipid PeroxidationLongitudinal StudiesMaleMalondialdehydeAntioxidantsBiomarkersMalondialdehydeNitratesNitric OxideNitritesantioxidantmalondialdehydenatural summer stressnitric oxideredox marker

Identifiers

PMID42254610
PMCPMC13236854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.