Evidence map›Paper›PMID 42254497›Full record

ReviewFrontiers in microbiology2026

Microbial contamination of medicines, medical devices, cosmetics, child and personal care products: a comprehensive review of secondary contamination risks in home-use settings.

Katia Iskandar, Loïc Marchin, Christine Roques

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katia IskandarDepartment of Biomedical Sciences, School of Pharmacy, Lebanese International University, Beirut, Lebanon.
Loïc MarchinPylote SAS, Dremil-Lafage, France.
Christine RoquesLaboratoire de Génie Chimique, CNRS, INPT, UPS, Faculté de Pharmacie, Université de Toulouse, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While various compliance with Good Manufacturing Practice and regulations ensures the safety and quality of manufactured products across the supply chain, the transition from controlled environment to home use represents a lurking hazard for microbial contamination, particularly among vulnerable populations. This comprehensive review examines the nature, extent, and clinical significance of microbial contamination in home-use medicines, medical devices, cosmetics, and personal care products, identifying common patterns and prevention strategies across product categories. Literature searches of PubMed, Web of Science, and Google Scholar identified studies examining secondary contamination of consumer-use products applied to skin and mucous membranes. Five categories were analyzed: medicines (eye drops, nasal irrigation devices), medical devices (nebulizers, breast pumps), infant care equipment (feeding bottles, pacifiers), cosmetics (mascara, lipsticks, eyeliners), and personal care products (contact lens cases, toothbrushes). Results showed that contamination rates ranged from 2 to 100% across products despite quality control and stringent regulation oversights. The predominant microbial contaminants were

Indexed as

biofilmhome-use productsmicrobial contaminationpatient safetypost-marketing surveillancesecondary contamination

Identifiers

PMID42254497
PMCPMC13233510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.