ArticleFrontiers in medicine2026
Application of deep learning methods in the classification of normal and pneumonia lung images.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Pneumonia remains a leading cause of morbidity and mortality worldwide, particularly in vulnerable populations. Rapid and accurate diagnosis through chest radiographs is essential, but manual interpretation can be subjective and time-consuming. This study aims to develop and evaluate deep learning-based models for the automated classification of chest X-ray images into normal and pneumonia categories, providing a foundation for a clinical decision support system. Methods: A retrospective dataset of 500 posterior-anterior chest X-rays (PA) from 2024 was used. Images were preprocessed and resized to 224 × 224 pixels. Four pre-trained convolutional neural network (CNN) architectures-VGG16, ResNet50, InceptionV3, and Xception-were fine-tuned using transfer learning. Model performance was evaluated using accuracy, precision, recall, F1-score, and area under the ROC curve (AUC). Results: Among the tested models, VGG16 achieved the highest test accuracy (87.1%) and AUC (0.92), demonstrating strong generalization and classification performance. InceptionV3 also performed well with 85.0% accuracy and AUC of 0.84. The Xception model reached an accuracy of 81.8% (AUC: 0.82) but showed low sensitivity in detecting pneumonia cases. ResNet50 underperformed with an accuracy of 74.2% and AUC of 0.81, likely due to class imbalance and overfitting. Conclusion: VGG16 and InceptionV3 demonstrated high potential for supporting pneumonia diagnosis in chest X-rays. Future research with larger, balanced, and multi-center datasets is needed to improve sensitivity and enhance clinical applicability.
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