Evidence map›Paper›PMID 42254380›Full record

ArticleFrontiers in medicine2026

CT-guided spinal nerve root adhesiolysis for refractory atypical symptoms in cervical disc herniation: a retrospective cohort study.

Qiong Xian, Yang Mao-Jiang, Yang Hong-Ying, Yang Han-Feng, Xu Xiao-Xue, Du Yong

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qiong Xian *Medical Education Center of Jinan University, Guangzhou, China.
Yang Mao-Jiang *Department of Pain, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Yang Hong-Ying *Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Yang Han-FengDepartment of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Xu Xiao-XueDepartment of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Du YongMedical Education Center of Jinan University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the clinical efficacy and safety of CT-guided spinal nerve root adhesiolysis in treating refractory atypical symptoms-specifically dizziness and tinnitus-in patients with cervical disc herniation (CDH). Methods: This retrospective cohort study included 256 patients with CDH presenting with persistent atypical symptoms who had failed conservative therapy for at least 3 months. All patients underwent CT-guided periradicular adhesiolysis involving the injection of an ozone-oxygen mixture, normal saline, and corticosteroids. Primary outcomes included symptom alleviation rates and functional improvements assessed via the Dizziness Handicap Inventory (DHI), Tinnitus Handicap Inventory (THI), Visual Analog Scale (VAS) for pain, and Neck Disability Index (NDI) at 1, 3, 6, and 12 months post-procedure. Results: At the 12-month follow-up, the intervention demonstrated significant efficacy. The alleviation rate for dizziness (baseline prevalence 85.2%) was 80.3%, and for tinnitus (baseline prevalence 68.8%) was 75.6%. Statistically significant improvements were observed in all functional scores compared to baseline ( Conclusion: For patients with CDH-related atypical symptoms refractory to conservative management, CT-guided spinal nerve root adhesiolysis is a safe and effective minimally invasive intervention. It provides sustained functional improvement and represents a vital therapeutic option for this challenging patient population.

Indexed as

atypical symptomscervical disc herniationCT-guidancedizzinessozonespinal nerve adhesiolysistinnitus

Identifiers

PMID42254380
PMCPMC13237678

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.