ArticleFrontiers in medicine2026
Age-related changes in central corneal thickness and their association with ocular biometric parameters in children.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Objective: To investigate age-related changes in central corneal thickness (CCT) and its relationship with ocular biometric parameters in children. Methods: This retrospective study included 393 children (786 eyes) examined using ZEISS IOLMaster 700 to measure CCT, axial length (AL), corneal curvature (Km), anterior chamber depth (ACD), and lens thickness (LT). Associations between CCT and age, sex, refractive status, and these biometric parameters were analyzed. Longitudinal CCT changes over 1 year were assessed in 158 children. Results: The cohort comprised 192 males (48.8%) and 201 females (51.2%) with a mean age of 9.5 ± 3.1 years and mean CCT of 551.53 ± 32.93 μm. CCT showed weak but significant positive correlations with age ( Conclusion: CCT increases with age in children aged 3-12 years and stabilizes after 13 years. Thinner CCT is associated with myopia and steeper corneal curvature, informing pediatric eye assessment, myopia management, and orthokeratology safety.
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