ArticleAnnals of medicine and surgery (2012)2026
National mortality trends associated with the death certificate-reported co-occurrence of malignant neoplasms and bacterial diseases in the United States, 1999-2023: a CDC WONDER retrospective analysis.
Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and objectives: Growing evidence suggests that bacterial infectious diseases contribute substantially to morbidity and mortality among individuals with malignant neoplasms. However, data regarding mortality related to the co-occurrence of malignant neoplasms and other bacterial diseases is limited. This study analyzes the national mortality trends for the co-occurrence of malignant neoplasms and other bacterial diseases in the United States from 1999 to 2023. Methods: A retrospective study was conducted using Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research mortality data for individuals aged 15+ to calculate age-adjusted mortality rates (AAMRs) per 100 000 and annual percent change (APC) using joinpoint regression, stratified by year, sex, age, race/ethnicity, urbanization, and geographic regions. Results: From 1999 to 2023, 726 510 deaths were recorded involving malignant neoplasms co-occurring with bacterial diseases. The AAMR slightly declined from 8.14 in 1999 to 7.63 in 2012, followed by a rise to 10.02 in 2023 with an APC of 2.51 (95% confidence interval: 2.14-2.89, Conclusion: Despite improvements, mortality from bacterial diseases and malignant neoplasms has increased, particularly affecting older adults, men, racial minorities, and the western region, requiring targeted interventions to reduce disease burden in vulnerable communities.
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