ArticleAnnals of medicine and surgery (2012)2026
Demographic trends in mortality related to Alzheimer's disease and pneumonia: a two-decade (1999-2022) analysis from the CDC WONDER database.
Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Pneumonia is a leading cause of death among Alzheimer's disease (AD) patients, often due to complications like sepsis or respiratory failure. This study aims to analyze the joint mortality patterns of AD and pneumonia to provide an accurate update on the public health impact and help uncover modifiable factors that could mitigate the disease burden. Methods: In this retrospective observational study, deidentified CDC WONDER death certificate data (1999-2022) were analyzed for individuals aged 65+ with ICD-10 codes for AD (G30) and pneumonia (J09-J18). To identify cases of AD and pneumonia, death records from the Multiple Causes of Death Public Use registry were reviewed, with these conditions listed as either a contributing or underlying cause of death. Mortality rates were calculated, and trends were evaluated using the Joinpoint Regression Program (National Cancer Institute). Results: From 1999 to 2022, the overall mean age-adjusted mortality rate (AAMR) for AD- and pneumonia-related deaths was 21.33 (95% CI: 17.91-24.75). The AAMR declined significantly from 37 in 1999 to 11.32 in 2016 (APC: -7.20, 95% CI: -12.97 to -5.47; Conclusion: Significant disparities in AD and pneumonia mortality highlight the need for targeted, community-focused interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.