Evidence map›Paper›PMID 42254128›Full record

ArticleAnnals of medicine and surgery (2012)2026

Comparison of crystalloid preloading and co-loading for the prevention of spinal induced-hypotension in elective cesarean delivery: a prospective cohort study.

Petros Baboker, Haile Demissie, Ermias Assefa, Natnael Tesfaye, Mulunesh Abebe, Ephrem Solomon, Dula Ababa, Dejene Gulilat, Kelil Musa

Abstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Petros BabokerDepartment of Anesthesia, College of Medicine and Health Science Wolkite University, Wolkite, Ethiopia.ORCID https://orcid.org/0009-0003-0318-0633
Haile DemissieDepartment of Anesthesia, College of Medicine and Health Science Wolkite University, Wolkite, Ethiopia.
Ermias AssefaDepartment of Anesthesia, College of Medicine and Health Science Arsi University, Arsi, Ethiopia.
Natnael TesfayeDepartment of Anesthesia, College of Medicine and Health Science Arsi University, Arsi, Ethiopia.
Mulunesh AbebeDepartment of Anesthesia, College of Medicine and Health Science Arsi University, Arsi, Ethiopia.
Ephrem SolomonDepartment of Anesthesia, College of Medicine and Health Science Arsi University, Arsi, Ethiopia.
Dula AbabaDepartment of Anesthesia, College of Medicine and Health Science Wollega University, Wollega, Ethiopia.
Dejene GulilatDepartment of Anesthesia, College of Medicine and Health Science Ambo University, Ambo, Ethiopia.
Kelil MusaDepartment of Anesthesia, College of Medicine and Health Science Ambo University, Madda walabu University, Bale Robe, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Maternal hypotension is the most frequent complication of spinal anesthesia for cesarean delivery. In this study, we assessed the effect of crystalloid preloading versus co-loading on the incidence of spinal anesthesia-induced hypotension in parturients undergoing elective cesarean delivery. Method: An institutional-based prospective cohort study was conducted. A total of 90 participants were divided into three groups: 30 participants in preload group (G1) given 1000 ml of normal saline 15 minutes before spinal anesthesia, 30 participants in co-load group (G2) given 1000 ml of normal saline fluid within 15 minutes together with spinal anesthesia, and 30 participants in the control group (G3) who were not given preloading or co-loading fluids. Statistical analysis for the differences among the three groups was analyzed using a repeated measure multivariate analysis of variance (MANOVA) test. The Bonferonni Result: In the current study, systolic blood pressure, diastolic blood pressure, and mean arterial pressure significantly decreased among the control groups compared with the co-load and preload groups, Conclusion: Based on the results of the current study, crystalloid fluid co-loading is more effective in reducing the incidence of hypotension after spinal anesthesia, reducing the need for a vasopressor and the occurrence of nausea and vomiting after spinal anesthesia in cesarean section parturients compared with preloading crystalloid fluid.

Indexed as

cohortco-loadcrystalloidhypotensionpreload

Identifiers

PMID42254128
PMCPMC13236303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.