Evidence map›Paper›PMID 42254120›Full record

ReviewAnnals of medicine and surgery (2012)2026

Epstein-Barr virus and oral health: epidemiology, pathogenesis, clinical aspects, and diagnostic insights: a narrative review.

Shyamkumar Sriram, Mambakkam Jayakanth, Sajad Ahmad Buch, Tanveer Alam, Shamimul Hasan

Abstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shyamkumar SriramDepartment of Rehabilitation and Health Services, College of Health and Public Service, University of North Texas, Denton, TX, USA.
Mambakkam JayakanthDepartment of Internal Medicine, Patiala Heart Institute, Patiala, India.
Sajad Ahmad BuchClinical Oral Health Sciences, School of Dentistry, IMU University, Federal Territory of Kuala Lumpur, Bukit Jalil, Malaysia.
Tanveer AlamDepartment of Biomedical Dental Sciences, College of Dentistry, Al Baha University, Alaqiq, Al Baha, Kingdom of Saudi Arabia.
Shamimul HasanDepartment of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India.ORCID https://orcid.org/0000-0001-6832-9150

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV), a widespread human herpesvirus, establishes lifelong latency and is linked to a range of systemic and oral diseases. Although primarily associated with infectious mononucleosis and lymphoproliferative disorders, its oral health implications are often overlooked. This review summarizes current insights into the epidemiology, pathogenesis, clinical aspects, and diagnostic methods of EBV in oral health. A comprehensive literature search using PubMed and Scopus databases identified studies focusing on EBV and its oral presentations, including keywords like "Epstein-Barr Virus," "oral health," "oral manifestations," "oral hairy leukoplakia," "periodontal disease," and "oral squamous cell carcinoma". EBV-related oral lesions include palatal petechiae, pharyngeal erythema, oral hairy leukoplakia, and ulcers, with emerging links to periodontal diseases and oral cancer. Diagnosis relies on clinical assessment, histopathology, polymerase chain reaction (PCR),

Indexed as

Epstein–Barr virusinfectious mononucleosisoral hairy leukoplakiaoral healthoral squamous cell carcinomaperiodontal diseases

Identifiers

PMID42254120
PMCPMC13236388

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.