Evidence map›Paper›PMID 42254087›Full record

ReviewJournal of transplantation2026

Living Donor Intestinal Transplant: Indication, Techniques, Surgical Complications, and Outcomes in Recipients and Donors: A Systematic Review.

Adil Nusair, Saad Bin Yousuf, Ahmed Adham R Elsayed, Marc D Basson

Abstract readReview
In one paragraph

Review in Journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adil NusairCollege of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, 44272, USA, neomed.edu.ORCID https://orcid.org/0009-0007-0281-4330
Saad Bin YousufCollege of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, 44272, USA, neomed.edu.ORCID https://orcid.org/0009-0009-6685-7609
Ahmed Adham R ElsayedCollege of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, 44272, USA, neomed.edu.ORCID https://orcid.org/0009-0005-7804-2344
Marc D BassonCollege of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, 44272, USA, neomed.edu.ORCID https://orcid.org/0000-0001-9696-2789

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Living donor intestinal transplantation (LDITx) is an alternative option to cadaveric transplants as a last resort in treating intestinal failure. There are limited data on LDITx outcomes. This systematic review evaluates LDITx in terms of indications, contraindications, surgical complications, and patient outcomes. Methods: A comprehensive search was conducted across PubMed, Cochrane Library, Virtual Health Library, and Web of Science databases following the PRISMA guidelines. After filtration, data were systematically extracted from all relevant observational studies, case series, and case reports. Quality assessments were performed using the CARE guideline for case reports and case series, while STROBE was used for observational studies. Results: Fifty-four studies were included, comprising 11 observational studies, 9 case series, and 34 case reports. The main indications of LDITx were the availability of a compatible donor and the urgency of the recipient's clinical condition. The standard surgical technique involves segmental ileal resection and transplantation. Postoperative complications included infections, ischemic events, and vascular complications. Recipients had either manageable complications or no complications. About 21.2% of the population experienced at least one episode of rejection, with an overall mortality rate of 23%. Many cases reported successful TPN weaning and good outcomes for the recipients and donors. Conclusion: In patients with chronic IF complicated by severe TPN-related morbidity or underlying pathologies causing SBS, LDITx represents an effective treatment option and an alternative to the more conventional cadaveric intestinal transplantation, bypassing problematic time sensitivity and donor availability.

Indexed as

intestinal failureintraoperative complicationsliving donor intestinal transplantpostoperative complicationsrisk factors

Identifiers

PMID42254087
PMCPMC13239233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.