Evidence map›Paper›PMID 42254079›Full record

ArticleJournal of nutrition and metabolism2026

Prevalence of Xerophthalmia and Associated Factors Among Pregnant Women in Tigray Region, Ethiopia.

Ebud Ayele Dagnazgi, Shewit Engdashet Berhe, Guesh Gebreayezgi, Goitom Girmay Gebremariam, Yohannes Kinfe Gebreyohannes, Tsega Gebremichael Gebremeskel, Embaba Tekelaye Welesemayat, Teklehaymanot Huluf Abraha, Gebregziabher Kidanemariam Asfaw

Abstract read
In one paragraph

Article in Journal of nutrition and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ebud Ayele DagnazgiDepartment of Public Health Nutrition, College of Medicine and Health Sciences, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0000-0003-3628-7886
Shewit Engdashet BerheDepartment of Public Health Nutrition, College of Medicine and Health Sciences, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0009-0009-1591-4554
Guesh GebreayezgiDepartment of Epidemiology and Biostatistics, College of Health Sciences, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0000-0002-9325-977X
Goitom Girmay GebremariamDepartment of Midwifery, College of Medicine and Health Science, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0000-0001-8503-8611
Yohannes Kinfe GebreyohannesDepartment of Epidemiology and Biostatistics, College of Health Sciences, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0000-0001-8529-9424
Tsega Gebremichael GebremeskelDepartment of Epidemiology and Biostatistics, College of Health Sciences, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0000-0001-8917-6974
Embaba Tekelaye WelesemayatDepartment of Epidemiology and Biostatistics, College of Health Sciences, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0000-0003-1591-1600
Teklehaymanot Huluf AbrahaDepartment of Reproductive & Family Health, College of Medicine and Health Science, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0000-0003-0868-1659
Gebregziabher Kidanemariam AsfawDepartment of Midwifery, College of Medicine and Health Science, Aksum University, Aksum, Ethiopia, aku.edu.et.ORCID https://orcid.org/0009-0008-9543-7630

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Xerophthalmia during pregnancy is a major public health problem, associated with an increased risk of morbidity and mortality among pregnant women. Studies indicated that Ethiopia is a country with the highest rates of xerophthalmia. However, most studies emphasize biochemical deficiency or night blindness rather than the full clinical spectrum. This study was intended to assess all clinical forms of xerophthalmia. Objective: The study assessed the prevalence and associated factors of xerophthalmia among pregnant women attending antenatal care in general and referral public hospitals of the Tigray Region, Ethiopia, in 2024. Methods: Using an institution-based cross-sectional design, a total of 1387 pregnant women were selected using a systematic random sampling technique to assess for xerophthalmia. The data collection was conducted from February 2024 to July 2024. Results were presented as adjusted odds ratios (AORs) with 95% CI and significance level Results: Out of the total 1387 selected pregnant women, 1355 participated, yielding a response rate of 97.83%. The prevalence of xerophthalmia was 25% (95% CI: 22.7%-27.3%). Factors significantly associated with xerophthalmia include inadequate sanitation (AOR = 2.369; 95% CI: 1.335-4.202), not taking iron supplementation (AOR = 2.577; 95% CI: 1.551-4.284), fewer antenatal care follow-ups (AOR = 3.462; 95% CI: 2.203-5.441), not owning livestock (AOR = 9.528; 95% CI: 5.666-16.023), history of miscarriage (AOR = 7.984; 95% CI: 4.361-14.614), alcohol consumption during pregnancy (AOR = 8.045; 95% CI: 3.94-16.425), consuming inadequate vegetables (AOR = 1.68; 95% CI: 1.18-2.40), and mid-upper arm circumference < 23 cm (AOR = 2.20; 95% CI: 1.58-3.08). Conclusions: Xerophthalmia among pregnant women in the Tigray Region indicates a critical public health concern. Inadequate sanitation, alcohol consumption during pregnancy, history of miscarriage, not owning livestock, low ANC attendance, inadequate vegetable consumption, undernutrition, and lack of iron supplementation during pregnancy were significantly associated with xerophthalmia. Therefore, we recommend adequate sanitation, avoiding alcohol consumption during pregnancy, preventing miscarriage, owning livestock in the household, ANC attendance, consuming vegetables, preventing acute malnutrition, and iron supplementation during pregnancy as effective interventions.

Indexed as

Ethiopiapregnant womenTigrayvitamin A deficiencyxerophthalmia

Identifiers

PMID42254079
PMCPMC13239026

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.