ArticleAnesthesiology research and practice2026
Ultrasound-Guided Pectoral Nerve Block for Cardiac Implantable Electronic Device Implantation: A Prospective Randomized Controlled Trial of Postprocedural Analgesic Benefit in an Asian Population.
Article in Anesthesiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Ultrasound-Guided Pectoral Nerve Block for Cardiac Implantable Electronic Device Implantation: A Prospective Randomized Controlled Trial of Postprocedural Analgesic Benefit in an Asian Population.Anesthesiology research and practice · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pain after cardiac implantable electronic device (CIED) implantation remains clinically relevant and may increase postoperative analgesic requirements. Ultrasound-guided pectoral nerve block has shown benefit in anterior chest wall procedures, but evidence during CIED implantation, particularly in Asian populations with relatively lower body mass index (BMI), remains limited. This study aimed to evaluate the efficacy and safety of ultrasound-guided pectoral nerve block for postoperative analgesia during CIED implantation and to explore clinical factors associated with rescue analgesic use. Methods: In this prospective randomized controlled trial, 660 patients undergoing CIED implantation were randomly assigned to a pectoral nerve block group or a standard-care group, with 330 patients in each group. Postoperative pain intensity was assessed using the numeric rating scale (NRS) at 1, 2, 4, 24, and 48 h after the procedure. Longitudinal NRS trajectories were analyzed using a linear mixed-effects model for repeated measures. Rescue analgesic use, length of hospital stay, and adverse events were compared between groups. Univariable and multivariable logistic regression analyses were performed as exploratory analyses to identify factors associated with rescue analgesic requirement. Results: Procedural characteristics were comparable between groups, including procedure type, device type, procedure duration, and implant laterality. Longitudinal analysis demonstrated significantly lower postoperative NRS scores over time in the pectoral nerve block group. Pain scores were consistently lower in the block group than in the control group at 1 h (0.87 ± 0.51 vs. 2.50 ± 0.78), 2 h (1.33 ± 0.55 vs. 4.37 ± 0.89), 4 h (2.00 ± 0.83 vs. 4.37 ± 0.93), 24 h (2.27 ± 0.91 vs. 4.57 ± 0.90), and 48 h (2.03 ± 0.67 vs. 3.67 ± 0.99) (all Conclusions: Ultrasound-guided pectoral nerve block significantly improved postoperative analgesia and reduced rescue analgesic use in patients undergoing CIED implantation without increasing adverse events. These findings support its use as an effective perioperative analgesic strategy in an Asian cohort with a relatively lower BMI profile and suggest that BMI-related variation in analgesic requirement may remain clinically relevant even in such populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.