Evidence map›Paper›PMID 42254008›Full record

ArticleFrontiers in immunology2026

Marcella Cipelli, Eloísa Martins da Silva, Lais Cavalieri Paredes, Mariana Abrantes do Amaral, Barbara Nunes Padovani, Luísa Menezes-Silva, Vinicius Andrade-Oliveira, Niels Olsen Saraiva Camara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcella CipelliDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Eloísa Martins da SilvaDepartment of Medicine, Discipline of Nephrology, Federal University of São Paulo, São Paulo, SP, Brazil.
Lais Cavalieri ParedesDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Mariana Abrantes do AmaralDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Barbara Nunes PadovaniDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Luísa Menezes-SilvaDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Vinicius Andrade-OliveiraCenter for Human and Natural Sciences, Federal University of ABC, São Paulo, SP, Brazil.
Niels Olsen Saraiva CamaraDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: RORγt Methods: Here, we developed and optimized an Results: The optimized protocol increased the frequency of RORγt Conclusion: This protocol enables the efficient

Indexed as

Immune ToleranceNuclear Receptor Subfamily 1, Group F, Member 3Oxidative PhosphorylationT-Lymphocytes, RegulatoryAnimalsCell DifferentiationCell ProliferationCells, CulturedLymphocyte ActivationMiceMice, Inbred C57BLNuclear Receptor Subfamily 1, Group F, Member 3immunometabolismRORγtT cell differentiationT cell functionTreg

Identifiers

PMID42254008
PMCPMC13233403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.