ArticleFrontiers in immunology2026
Impact of in ovo myo-inositol administration on immune modulation in broiler chickens.
Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
Myo-inositol (MI) plays an important role in intracellular signaling, cell proliferation, and cell growth, and has been associated with positive effects on the immune system and health in fish. However, its potential immunological effects in poultry have not been investigated yet. This study aimed to evaluate the effects of in ovo MI administration on immune parameters in broiler chickens after hatching. A total of 480 fertilized Ross 308 eggs were randomly assigned as hatched to four groups and injected on embryonic day 17 with either 12 µmol/mL MI (MI-12), 24 µmol/mL MI (MI-24), 0.9% saline (positive control, PC), or left untreated (negative control, NC). After hatching, broilers were housed in floor pens. On day 35, eight birds per treatment group were sampled for analysis of leukocyte subsets and antibody concentrations in blood. Overall, in ovo MI administration had only slight effects on the immune parameters. Birds in the MI-24 group had lower plasma IgM concentrations and showed a tendency toward lower CD4
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