Evidence map›Paper›PMID 42253935›Full record

ArticleMedComm2026

Trends in Asthma-Rhinitis Allergic Multimorbidity and Polysensitization in China: The CARRAD Study.

Wanjun Wang, Jianhong Wang, Guihua Song, Hua Xie, Rongfei Zhu, Yong He, Jun Tang, Junge Wang, Jinghua Yang, Lili Zhi and 32 more

Abstract read
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

Wanjun WangDepartment of Allergy and Clinical Immunology National Clinical Research Center for Respiratory Disease State Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Jianhong WangThe First People's Hospital of Yibin Yibin China.
Guihua SongThe First Affiliated Hospital of Henan University of Traditional Chinese Medicine Zhengzhou Henan China.
Hua XieGeneral Hospital of Northern Theater Command Shenyang China.
Rongfei ZhuTongji Hospital Tongji Medical College Huazhong University of Science & Technology Wuhan China.
Yong HeThe Affiliated Hospital of Medical School Ningbo University Ningbo China.
Jun TangFoshan First People's Hospital Foshan China.
Junge WangBeijing Hospital of Traditional Chinese Medicine Beijing China.
Jinghua YangGuangdong Provincial Hospital of Chinese Medicine Guangzhou China.
Lili ZhiThe First Affiliated Hospital of Shandong First Medical University Shandong Institute of Respiratory Diseases Taian China.
Lin WuHangzhou Hospital of Traditional Chinese Medicine Hangzhou China.
Yan JiangThe Affiliated Hospital of Qingdao University Qingdao China.
Xiaoqin ZhouHubei Province Maternal and Child Health Hospital Hubei China.
Dongming HuangBoai Hospital of Zhongshan City Zhongshan China.
Ning WangXi'an Children's Hospital Xi'an China.
Rui XuThe First Affiliated Hospital of Sun Yat-Sen University Guangzhou China.
Yuan GaoThe First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Zhimin ChenChildren's Hospital of Zhejiang University School of Medicine National Clinical Research Center for Child Health Hangzhou China.
Xiaoli HanHebei General Hospital Hebei China.
Guolin TanThird Xiangya Hospital of Central South University Changsha China.
Jinzhun WuThe Women and Children's Hospital Affiliated to Xiamen University Xiamen China.
Deyu ZhaoChildren's Hospital of Nanjing Medical University Nanjing China.
Jianjun ChenUnion Hospital of Tongji Medical College Wuhan China.
Weixi ZhangThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou China.
Yuemei SunYu Huang Ding Hospital Yantai China.
Yi JiangThe First Hospital of Shanxi Medical University Taiyuan China.
Weitian ZhangShanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China.
Qianhui QiuZhujiang Hospital of Southern Medical University Guangzhou China.
Chuanhe LiuChildren's Hospital Capital Institute of Pediatrics Beijing China.
Jie YinChengdu First People's Hospital Chengdu China.
Guodong HaoTangshan Gongren Hospital Tangshan China.
Huabin LiENT Institute and Department of Otorhinolaryngology Eye & ENT Hospital Fudan University Shanghai China.
Yongsheng XuChildren's Hospital of Tianjin University Tianjin China.
Shaohua ChenGuangdong Provincial People's Hospital Guangzhou China.
Shi ChenHainan Provincial People's Hospital Haikou China.
Juan MengWest China Hospital of Sichuan University Chengdu China.
Dan ZengChongqing General Hospital University of Chinese Academy of Sciences Chongqing China.
Wei TangRuijin Hospital of Shanghai Jiaotong University Shanghai China.
Chuangli HaoChildren's Hospital of Soochow University Suzhou China.
Nanshan ZhongDepartment of Allergy and Clinical Immunology National Clinical Research Center for Respiratory Disease State Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Jing LiDepartment of Allergy and Clinical Immunology National Clinical Research Center for Respiratory Disease State Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
China Alliance of Research on Respiratory Allergic Disease (CARRAD)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The trends in allergic comorbidities secondary to the environmental variations in China remain unclear. We aimed to determine the variation of allergic comorbidities and polysensitization among asthma and/or rhinitis patients in the past decade. We assessed two nationally representative cross-sectional datasets from 2008 to 2009 and 2018 to 2019, which enrolled 2322 and 2353 patients, respectively. Over the present 10-year study period, the prevalence of allergic symptoms and allergen sensitivity among patients with multiple sensitivities in the 2018-2019 cohort was significantly higher than that in the 2008-2009 cohort, especially for mites, pollen, and animal allergens. The comorbidity rates of asthma, allergic rhinitis, conjunctivitis, and eczema were significantly increased in the 2018-2019 cohort. Also in that cohort, IgE polysensitization was significantly associated with the coexistence of asthma and rhinitis, and the number of IgE-reactive allergens was significantly associated with the number of multimorbidities. Use of an air-conditioner and carpet in the home, and keeping pet were linked to the risk of polysensitization. Our findings suggest an increase in the comorbidity rate and multimorbid polysensitized phenotype of allergic diseases in China. Asthma occurred in both cohorts more frequently with coexisting allergies than as a single entity.

Indexed as

allergic comorbiditiesallergic rhinitisasthmaepidemiologypolysensitization

Identifiers

PMID42253935
PMCPMC13238639

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.