Evidence map›Paper›PMID 42253869›Full record

ArticleRadiology case reports2026

A rare case presentation of a common condition: A large laryngeal gouty tophus.

Habib Hassan, Salman Waheeduddin, William Macdonald

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Habib HassanDiagnostic Radiology, Aurora St. Luke's Medical Center, 2900 W Oklahoma Ave, Milwaukee, WI 53215.
Salman WaheeduddinDiagnostic Radiology, Aurora St. Luke's Medical Center, 2900 W Oklahoma Ave, Milwaukee, WI 53215.
William MacdonaldDiagnostic Radiology, Aurora St. Luke's Medical Center, 2900 W Oklahoma Ave, Milwaukee, WI 53215.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laryngeal gout is an exceedingly rare manifestation of advanced, poorly controlled gout. It is characterized by the deposition of gouty tophi within various laryngeal structures. Similar to peripheral joints, monosodium urate crystals develop due to high concentrations of serum uric acid. When localized to the laryngeal region, tophi can induce a range of symptoms and complications, including hoarseness, dysphagia, respiratory distress, and infection. Alternatively, it may present as an asymptomatic anterior neck mass. The thyroid cartilage, true vocal cords, arytenoids, and cricoarytenoid joints have all been previously described as areas of involvement. In this case report, we describe the presence of a large, asymptomatic laryngeal gouty tophus situated between the hyoid bone and thyroid cartilage that was initially interpreted as ectopic thyroid tissue on CT imaging. Management typically includes urate-lowering therapy, reduction in alcohol and red meat consumption, and potential surgical intervention for obstructive symptoms. This case underscores the importance of considering laryngeal gouty tophi in patients with chronically uncontrolled hyperuricemia presenting with anterior neck masses.

Indexed as

GoutHmongLaryngeal GoutLaryngeal gouty tophus

Identifiers

PMID42253869
PMCPMC13233749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.