Evidence map›Paper›PMID 42253848›Full record

ReviewPolymer science & technology (Washington, D.C.)2026

Organic Semiconducting Polymers for Cancer Sonodynamic Immunotherapy.

Peiting Hu, Shasha He, Huayu Tian

Abstract readReview
In one paragraph

Review in Polymer science & technology (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peiting HuCollege of Chemistry and Chemical Engineering, Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, Xiamen University, Xiamen 361005, China.
Shasha HeCollege of Chemistry and Chemical Engineering, Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, Xiamen University, Xiamen 361005, China.ORCID https://orcid.org/0000-0003-0079-8625
Huayu TianCollege of Chemistry and Chemical Engineering, Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, Xiamen University, Xiamen 361005, China.ORCID https://orcid.org/0000-0002-2482-3744

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer immunotherapy has attracted significant attention in recent years for its ability to harness the patient's own immune system to target and eliminate tumors. Despite its promise, major challenges remain, including low tumor immunogenicity, immunosuppressive tumor microenvironments, and systemic toxicities. To address these issues, activatable immunotherapy strategies have been developed, enabling the precise activation of immune agents in response to specific endogenous or exogenous signals. Among these approaches, ultrasound-triggered sonodynamic therapy (SDT) has emerged as a promising non-invasive modality, offering deep tissue penetration and spatiotemporal precision. Organic semiconducting polymers (SPs), as a class of sonosensitizers, exhibit excellent acoustic responsiveness, biocompatibility, and structural tunability, making them ideal candidates for tumor-targeted SDT. This Review highlights recent advances in the application of organic semiconducting polymers in cancer immunotherapy, discusses current challenges, and explores future directions for developing more precise and low-toxicity therapeutic strategies.

Indexed as

cancer immunotherapycombination therapyimmunogenic cell deathintelligent release mechanismorganic semiconducting polymersreactive oxygen speciessonodynamic therapysonosensitizers

Identifiers

PMID42253848
PMCPMC13052588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.