Evidence map›Paper›PMID 42253821›Full record

ArticleBrain & spine2026

From planning to execution: Interactive virtual-reality assisted craniotomy planning in meningioma surgery.

Sebastian Lehmann, Martin Vychopen, Alexandru Guranda, Florian Wilhelmy, Ferdinand Weber, Johannes Wach, Erdem Güresir

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Article in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Sebastian LehmannDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany.
Martin VychopenDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany.
Alexandru GurandaDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany.
Florian WilhelmyDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany.
Ferdinand WeberDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany.
Johannes WachDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany.
Erdem GüresirDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, 04103, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In meningioma surgery, extent and accuracy of the craniotomy are vital to achieve the predefined extent of resection. We routinely integrate interactive virtual-reality (iVR) assistance into craniotomy planning. Research question: Are preoperatively iVR-planned approaches transferable to craniotomies subsequently performed in the operating room? Material and methods: We examined 83 patients surgically treated with meningiomas, where the approach strategy was preoperatively planned and demonstrated using the MagicLeap 2 or HoloLens 2. The iVR-planned approach (iVR-Group) was compared to the real craniotomy (Real-Group) by location and relative size of craniotomy, as well as position and number of burr holes. Results: When comparing the craniotomy size, the mean anterior-posterior (AP)-ratio was 0.40 in iVR-group vs 0.41 in Real-group with 17.5% mean deviation, while the mean lateral ratio was 0.45 vs 0.49 with 15.9% mean deviation.In 9.6% of procedures, a diverging number of burr holes were used, in 3.6% the position was altered from iVR-group to Real-group. In testing for equality (TOST-test) both AP and lateral-ratio deviation showed significant results: AP-ratio-deviation: p = 0.015, CI: -0.047-0.013, equivalence margin ±0.059; lateral ratio-deviation p = 0.041, CI: -0.068-0.004, equivalence margin ±0.071. The geometrical index was 0.423 for iVR group and 0.448 for Real-group. The percentage deviation between both groups was 5.9%, indicating high transferability of preoperative planning. Discussion and conclusion: With state-of-the-art iVR-planning of meningioma surgery approaches, craniotomies respecting pathological and anatomical relations and conflicts can be accurately simulated. IVR planning may mark a new level of interactive learning and strategic planning in neurosurgery.

Indexed as

Approach planningAugmented realityCraniotomyMeningiomaMixed realityVirtual reality

Identifiers

PMID42253821
PMCPMC13235324

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.