ArticleGeneral psychiatry2026
Bilateral repetitive transcranial magnetic stimulation modulates the hemispheric imbalance in major depressive disorder.
Article in General psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Bilateral repetitive transcranial magnetic stimulation modulates the hemispheric imbalance in major depressive disorder.General psychiatry · 2026Article
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Authors and funding
8 authors.
Funding
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Abstract
Background: Major depressive disorder (MDD) is characterised by interhemispheric functional imbalance, yet the neuromodulatory mechanisms underlying its correction remain poorly understood. Repetitive transcranial magnetic stimulation (rTMS) has shown promise in restoring hemispheric balance, but evidence regarding its effects on alpha-band functional connectivity (FC) is limited. Aims: This randomised, two-arm controlled trial aims to elucidate the neural mechanisms by which bilateral rTMS ameliorates interhemispheric functional imbalance in patients with MDD by reducing alpha-band functional hyperconnectivity in the left hemisphere. Methods: Fifty-two patients with MDD were randomised to active ( Results: Active rTMS significantly improved sleep quality (PSQI, Conclusions: Bilateral rTMS modulates interhemispheric imbalance in patients with MDD by reducing pathological alpha-band FC in left hemispheric regions, which is correlated with improved emotional processing and attentional performance. These findings support the use of alpha-band FC as a biomarker for rTMS efficacy and highlight the potential of network-targeted stimulation protocols for the individualised treatment of MDD.
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