Evidence map›Paper›PMID 42253749›Full record

ArticleCase reports in cardiology2026

Revealing the Hidden Severity: A Case Report on Managing Complex Aortic Stenosis With TAVI.

Thomas Stefoulis, James Sindone, Mahiar Mahjoub, Samuel Jay-Jackson Pack, Sean Lal

Abstract read
In one paragraph

Article in Case reports in cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas StefoulisJunior Medical Workforce, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia, nsw.gov.au.ORCID https://orcid.org/0000-0002-9655-1741
James SindoneCardiology Department, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia, nsw.gov.au.ORCID https://orcid.org/0000-0002-7564-0737
Mahiar MahjoubJunior Medical Workforce, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia, nsw.gov.au.ORCID https://orcid.org/0000-0003-0951-9629
Samuel Jay-Jackson PackJunior Medical Workforce, Bankstown Hospital, Sydney, New South Wales, Australia.ORCID https://orcid.org/0009-0001-2001-6347
Sean LalCardiology Department, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia, nsw.gov.au.ORCID https://orcid.org/0000-0002-5841-560X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic stenosis (AS) is a progressive condition prevalent in older adults, with severity determined through clinical evaluation and imaging. However, diagnostic dilemmas arise when imaging results conflict with clinical symptoms. This report examines an 84-year-old male with chronic kidney disease, prior abdominal aortic aneurysm repair and other comorbidities, presenting with decompensated heart failure. Initial echocardiography findings suggested moderate AS, insufficient to qualify for transcatheter aortic valve implantation (TAVI) under national guidelines, despite clinical evidence of worsening heart failure. A multimodal diagnostic approach, incorporating Agatston scoring, dobutamine stress echocardiography (DSE), and invasive haemodynamics, was undertaken to resolve this discordance. DSE demonstrated persistent discordance between Doppler- and Simpson-derived flow estimates, whereas CT calcium scoring and left heart catheterisation ultimately confirmed severe AS, with an aortic valve area of 0.75 cm

Indexed as

Agatston scoreaortic stenosiscase reportmultimodal diagnostic approachTAVIvalvular disease

Identifiers

PMID42253749
PMCPMC13239360

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.