Evidence map›Paper›PMID 42253740›Full record

ArticleFrontiers in nutrition2026

Functional processing enhances hepatic targeting: the OAT2/MRP2 mechanism of vinegar-processed Cyperi Rhizoma.

Gui Xu, Yang Chen, Shiru Jiang, Shuo Zhang, Xiutong Ge, Fan Zhang, Hui Gao

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gui XuSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning, China.
Yang ChenSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning, China.
Shiru JiangSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning, China.
Shuo ZhangSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning, China.
Xiutong GeSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning, China.
Fan ZhangSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning, China.
Hui GaoSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Processing techniques play a critical role in modifying the bioavailability of botanical ingredients. Traditional processing theory suggests that vinegar processing enhances the hepatic-targeting effects of Cyperi Rhizoma (CR), a botanical used in functional foods and traditional medicine. However, the molecular mechanism remains largely unexplored. This study integrated in silico docking with

Indexed as

cyperotundoneCyperus rotundusfunctional foodliver-targeting mechanismorganic anion transporter

Identifiers

PMID42253740
PMCPMC13233250

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.