ArticleInternational journal of surgery case reports2026
Nasal floor wound coverage with an absorbable collagen matrix after revision endoscopic transsphenoidal surgery: a case report.
Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction and importance: Absorbable collagen matrices are widely used for dural repair in neurosurgery, but their application as wound dressings in the sinonasal cavity has not been reported. Donor-site morbidity after nasoseptal flap (NSF) harvest remains a clinical challenge, particularly in revision cases with limited residual mucosa. Case presentation: An 82-year-old woman with two prior transsphenoidal surgeries (15 and 11 years prior) for a clinically nonfunctioning pituitary neuroendocrine tumor presented with progressive bitemporal hemianopsia. Imaging revealed a 37-mm recurrent sellar/suprasellar mass and near-total loss of the nasal septum. Revision surgery was pursued, given her adequate general condition and progressive optic apparatus compression. Extended NSF harvest left the nasal floor bone exposed, for which autologous donor mucosa was unavailable; an absorbable collagen matrix (DuraGen) was placed as a temporary wound dressing and secured with fibrin glue. Endoscopy on postoperative day (POD) 8 showed matrix adherence with granulation tissue. At POD 28, stable crusted coverage without infection was observed. At 3 months, the nasal floor mucosa appeared regenerated on otorhinolaryngology examination. Clinical discussion: Existing donor-site coverage strategies require harvestable autologous tissue, which was unavailable in this revision setting. The collagen matrix appeared to function as a temporary scaffold during early healing, although accelerated remucosalization could not be objectively confirmed. Conclusion: Off-label collagen matrix placement over exposed nasal floor bone was technically feasible, followed by an uncomplicated course with apparent mucosal regeneration at 3 months, and should be regarded as investigational pending prospective comparative studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.