ArticleAsia-Pacific journal of oncology nursing2026
Family care and social alienation in patients with colorectal cancer and an ostomy: The sequential mediating effects of resilience and stigma.
Article in Asia-Pacific journal of oncology nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to examine the association between family care and social alienation among patients with colorectal cancer (CRC) and an ostomy, and to explore the sequential mediating roles of resilience and stigma based on the ABC-X model. Methods: A cross-sectional study was conducted among 290 CRC patients with an ostomy in Fujian Province, China from October 2024 to August 2025. The participants completed questionnaires assessing family care, resilience, stigma, and social alienation. Serial multiple mediation analysis using the PROCESS macro tested the hypothesized pathways. Bootstrapping with 5000 resamples and bias-corrected 95% confidence intervals was used for testing the significance of indirect effects. Results: Family care negatively correlated with social alienation ( Conclusions: Family care was associated with lower social alienation among CRC patients with an ostomy, potentially through higher resilience and lower stigma. These findings highlight the important role of family-based psychosocial resources in promoting adaptive adjustment following body-altering surgery. Nursing interventions should prioritize strengthening family care, cultivating resilience, and reducing illness-related stigma to promote social reintegration and overall well-being in CRC patients with an ostomy.
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